| Teams 2000 OReilly 400 |
|---|
| No. | Team | Driver | Mfg |
|---|---|---|---|
| 1 | K-Automotive Performance | Dennis Setzer | Dodge |
| 2 | Ultra Motorsports | Mike Wallace | Ford |
| 3 | Team Menard | Bryan Reffner | Chevrolet |
| 5 | Ultra Motorsports | Eric Norris | Ford |
| 7 | PF2 Motorsports | Randy Renfrow | Chevrolet |
| 12 | Impact Motorsports | Carlos Contreras | Dodge |
| 14 | Circle Bar Racing | Rick Crawford | Ford |
| 16 | Team Rensi Motorsports | Jimmy Hensley | Chevrolet |
| 17 | Hendrick Motorsports | Ricky Hendrick | Chevrolet |
| 18 | Bobby Hamilton Racing | Joe Ruttman | Dodge |
| 20 | Joe Gibbs Racing | Coy Gibbs | Chevrolet |
| 24 | Hendrick Motorsports | Jack Sprague | Chevrolet |
| 25 | Impact Motorsports | Randy Tolsma | Chevrolet |
| 26 | MB Motorsports | Tony Roper | Ford |
| 27 | CJ Racing | Ricky Sanders | Ford |
| 31 | Brevak Racing | Larry Gunselman | Ford |
| 38 | Jeff Russell | Patrick Lawler | Chevrolet |
| 41 | TKO Motorsports | David Starr | Dodge |
| 43 | Petty Enterprises | Steve Grissom | Dodge |
| 44 | Petty Brothers Racing | Mark Petty | Dodge |
| 46 | Dollar Racing | Rob Morgan | Ford |
| 50 | Roush Racing | Greg Biffle | Ford |
| 51 | Rick Ware Racing | Rick Ware | Chevrolet |
| 53 | Horn Auto Racing | Chris Horn | Chevrolet |
| 54 | Sockwell Racing | Brian Sockwell | Chevrolet |
| 60 | Addington Racing | Andy Houston | Chevrolet |
| 61 | Team Rensi Motorsports | Chad Chaffin | Chevrolet |
| 66 | Phelon Motorsports | Rick Carelli | Ford |
| 71 | Rowland Racing | Tommy Croft | Chevrolet |
| 72 | MacDonald Motorsports | Randy MacDonald | Chevrolet |
| 73 | Sonntag Racing | B.A. Wilson | Chevrolet |
| 75 | Spears Motorsports | Marty Houston | Chevrolet |
| 86 | Impact Motorsports | Derrike Cope | Dodge |
| 88 | ThorSport Racing | Terry Cook | Chevrolet |
| 90 | L & R Motorsports | Lance Norick | Chevrolet |
| 99 | Roush Racing | Kurt Busch | Ford |