| Teams for 2000 OReilly 400 |
|---|
| Car | Team | Driver | Mfg |
|---|---|---|---|
| 1 | Bob Keselowski | Dennis Setzer |  |
| 2 | Ultra Motorsports | Mike Wallace |  |
| 3 | Team Menard | Bryan Reffner |  |
| 5 | Ultra Motorsports | Eric Norris | |
| 7 | Conley Motorsports | Randy Renfrow | |
| 12 | Impact Motorsports | Carlos Contreras | |
| 14 | Tom Mitchell | Rick Crawford | |
| 16 | Ed Rensi | Jimmy Hensley | |
| 17 | Rick Hendrick | Ricky Hendrick | |
| 18 | Bobby Hamilton | Joe Ruttman | |
| 20 | Joe Gibbs | Coy Gibbs | |
| 24 | Rick Hendrick | Jack Sprague | |
| 25 | Impact Motorsports | Randy Tolsma | |
| 26 | MB Motorsports | Tony Roper | |
| 27 | Mike Albernaz | Ricky Sanders | |
| 31 | Brevak Racing | Larry Gunselman | |
| 38 | Jeff Russell | Patrick Lawler | |
| 41 | TKO Motorsports | David Starr | |
| 43 | Richard Petty | Steve Grissom | |
| 44 | Maurice Petty | Mark Petty | |
| 46 | Dollar Racing | Rob Morgan | |
| 50 | Jack Roush | Greg Biffle | |
| 51 | Rick Ware | Rick Ware | |
| 53 | Horn Auto Racing | Chris Horn | |
| 54 | Dennis Sockwell | Brian Sockwell | |
| 60 | Mike Addington | Andy Houston | |
| 61 | Ed Rensi | Chad Chaffin | |
| 66 | Phelon Motorsports | Rick Carelli | |
| 71 | Stanley Rowland | Tommy Croft | |
| 72 | MacDonald Motorsports | Randy MacDonald | |
| 73 | Sonntag Racing | B.A. Wilson | |
| 75 | Wayne Spears | Marty Houston | |
| 86 | Impact Motorsports | Derrike Cope | |
| 88 | SealMaster Racing | Terry Cook | |
| 90 | L & R Motorsports | Lance Norick | |
| 99 | Jack Roush | Kurt Busch | |
