| Teams 2018 Drive for the Cure 300 Presented by Blue Cross Blue Shield of NC |
|---|
| No. | Team | Driver | Mfg |
|---|---|---|---|
| 0 | Stewart Haas Racing | Cole Custer | Ford |
| 0 | JD Motorsports | Garrett Smithley | Chevrolet |
| 1 | JR Motorsports | Elliott Sadler | Chevrolet |
| 1 | JD Motorsports | Lawson Aschenbach | Chevrolet |
| 2 | Richard Childress Racing | Matt Tifft | Chevrolet |
| 3 | Richard Childress Racing | Brendan Gaughan | Chevrolet |
| 4 | JD Motorsports | Ross Chastain | Chevrolet |
| 5 | JR Motorsports | Michael Annett | Chevrolet |
| 07 | SS Green Light Racing | Spencer Boyd | Chevrolet |
| 7 | JR Motorsports | Justin Allgaier | Chevrolet |
| 8 | BJ McLeod Motorsports | Dylan Murcott | Chevrolet |
| 9 | JR Motorsports | Tyler Reddick | Chevrolet |
| 11 | Kaulig Racing | Ryan Truex | Chevrolet |
| 13 | MBM Motorsports / Garage 66 | Landon Cassill | Dodge |
| 15 | JD Motorsports | Katherine Legge | Chevrolet |
| 16 | Roush Fenway Racing | Ryan Reed | Ford |
| 18 | Joe Gibbs Racing | Ryan Preece | Toyota |
| 19 | Joe Gibbs Racing | Brandon Jones | Toyota |
| 20 | Joe Gibbs Racing | Christopher Bell | Toyota |
| 21 | Richard Childress Racing | Daniel Hemric | Chevrolet |
| 22 | Team Penske | Austin Cindric | Ford |
| 23 | GMS Racing | Spencer Gallagher | Chevrolet |
| 35 | Go Green Racing | Joey Gase | Chevrolet |
| 36 | DGM Racing | Alex Labbe | Chevrolet |
| 38 | RSS Racing | JJ Yeley | Chevrolet |
| 39 | RSS Racing | Ryan Sieg | Chevrolet |
| 40 | MBM Motorsports / Garage 66 | Chad Finchum | Dodge |
| 42 | Chip Ganassi Racing | Justin Marks | Chevrolet |
| 45 | JP Motorsports | Josh Bilicki | Toyota |
| 51 | Jeremy Clements Racing | Jeremy Clements | Chevrolet |
| 52 | Jimmy Means Racing | David Starr | Chevrolet |
| 55 | JP Motorsports | Bayley Currey | Toyota |
| 60 | Roush Fenway Racing | Ty Majeski | Ford |
| 61 | Fury Race Cars LLC | Kaz Grala | Ford |
| 66 | MBM Motorsports / Garage 66 | Timmy Hill | Toyota |
| 74 | BJ McLeod Motorsports | Ray Black, Jr. | Chevrolet |
| 78 | BJ McLeod Motorsports | Vinnie Miller | Chevrolet |
| 90 | DGM Racing | Andy Lally | Chevrolet |
| 93 | RSS Racing | Jeff Green | Chevrolet |
| 98 | Biagi DenBeste Racing | Chase Briscoe | Ford |