| Teams 2021 ToyotaCare 250 |
|---|
| No. | Team | Driver | Mfg |
|---|---|---|---|
| 1 | TRICON Garage | Hailie Deegan | Ford |
| 2 | GMS Racing | Sheldon Creed | Chevrolet |
| 02 | Youngs Motorsports | Kris Wright | Chevrolet |
| 3 | Jordan Anderson Racing | Howie Disavino III | Chevrolet |
| 04 | Roper Racing | Cory Roper | Ford |
| 4 | Kyle Busch Motorsports | John H. Nemechek | Toyota |
| 6 | Norm Benning Racing | Norm Benning | Chevrolet |
| 9 | CR7 Motorsports | Codie Rohrbaugh | Chevrolet |
| 10 | Jennifer Jo Cobb Racing | Jennifer Jo Cobb | Chevrolet |
| 11 | Spencer Davis Motorsports | Spencer Davis | Toyota |
| 12 | Youngs Motorsports | Tate Fogleman | Chevrolet |
| 13 | ThorSport Racing | Johnny Sauter | Toyota |
| 15 | TRICON Garage | Tanner Gray | Ford |
| 16 | Hattori Racing Enterprises | Austin Hill | Toyota |
| 18 | Kyle Busch Motorsports | Chandler Smith | Toyota |
| 19 | McAnally Hilgemann Racing | Derek Kraus | Toyota |
| 20 | Youngs Motorsports | Spencer Boyd | Chevrolet |
| 21 | GMS Racing | Zane Smith | Chevrolet |
| 22 | AM Racing | Austin Wayne Self | Chevrolet |
| 23 | GMS Racing | Chase Purdy | Chevrolet |
| 24 | GMS Racing | Raphael Lessard | Chevrolet |
| 25 | Rackley W.A.R. | Timothy Peters | Chevrolet |
| 26 | GMS Racing | Tyler Ankrum | Chevrolet |
| 30 | On Point Motorsports | Danny Bohn | Toyota |
| 32 | Bret Holmes Racing | Sam Mayer | Chevrolet |
| 33 | Team Reaume | Keith McGee | Chevrolet |
| 34 | Team Reaume | Josh Reaume | Toyota |
| 38 | Front Row Motorsports | Todd Gilliland | Ford |
| 40 | Niece Motorsports | Ryan Truex | Chevrolet |
| 41 | Cram Racing Enterprises | Dawson Cram | Chevrolet |
| 42 | Niece Motorsports | Carson Hocevar | Chevrolet |
| 44 | Niece Motorsports | Jett Noland | Chevrolet |
| 45 | Niece Motorsports | Brett Moffitt | Chevrolet |
| 49 | CMI Motorsports | Ryan Reed | Chevrolet |
| 51 | Kyle Busch Motorsports | Kyle Busch | Toyota |
| 52 | Halmar Friesen Racing | Stewart Friesen | Toyota |
| 56 | Hill Motorsports | Timmy Hill | Chevrolet |
| 88 | ThorSport Racing | Matt Crafton | Toyota |
| 98 | ThorSport Racing | Grant Enfinger | Toyota |
| 99 | ThorSport Racing | Ben Rhodes | Toyota |