| Teams 2025 South Point 400 |
|---|
| No. | Team | Driver | Mfg |
|---|---|---|---|
| 1 | Trackhouse Racing | Ross Chastain | Chevrolet |
| 2 | Team Penske | Austin Cindric | Ford |
| 3 | Richard Childress Racing | Austin Dillon | Chevrolet |
| 4 | Front Row Motorsports | Noah Gragson | Ford |
| 5 | Hendrick Motorsports | Kyle Larson | Chevrolet |
| 6 | RFK Racing | Brad Keselowski | Ford |
| 7 | Spire Motorsports | Justin Haley | Chevrolet |
| 8 | Richard Childress Racing | Kyle Busch | Chevrolet |
| 9 | Hendrick Motorsports | Chase Elliott | Chevrolet |
| 10 | Kaulig Racing | Ty Dillon | Chevrolet |
| 11 | Joe Gibbs Racing | Denny Hamlin | Toyota |
| 12 | Team Penske | Ryan Blaney | Ford |
| 16 | Kaulig Racing | AJ Allmendinger | Chevrolet |
| 17 | RFK Racing | Chris Buescher | Ford |
| 19 | Joe Gibbs Racing | Chase Briscoe | Toyota |
| 20 | Joe Gibbs Racing | Christopher Bell | Toyota |
| 21 | Wood Brothers Racing | Josh Berry | Ford |
| 22 | Team Penske | Joey Logano | Ford |
| 23 | 23XI Racing | Bubba Wallace | Toyota |
| 24 | Hendrick Motorsports | William Byron | Chevrolet |
| 34 | Front Row Motorsports | Todd Gilliland | Ford |
| 35 | 23XI Racing | Riley Herbst | Toyota |
| 38 | Front Row Motorsports | Zane Smith | Ford |
| 41 | Haas Factory Team | Cole Custer | Ford |
| 42 | Legacy Motor Club | John H. Nemechek | Toyota |
| 43 | Legacy Motor Club | Erik Jones | Toyota |
| 44 | NY Racing Team | JJ Yeley | Chevrolet |
| 45 | 23XI Racing | Tyler Reddick | Toyota |
| 47 | Hyak Motorsports | Ricky Stenhouse, Jr. | Chevrolet |
| 48 | Hendrick Motorsports | Alex Bowman | Chevrolet |
| 51 | Rick Ware Racing | Cody Ware | Ford |
| 54 | Joe Gibbs Racing | Ty Gibbs | Toyota |
| 60 | RFK Racing | Ryan Preece | Ford |
| 71 | Spire Motorsports | Michael McDowell | Chevrolet |
| 77 | Spire Motorsports | Carson Hocevar | Chevrolet |
| 78 | Live Fast Motorsports | Katherine Legge | Chevrolet |
| 88 | Trackhouse Racing | Shane Van Gisbergen | Chevrolet |
| 99 | Trackhouse Racing | Daniel Suarez | Chevrolet |